What is Relion Novolin N?
Relion Novolin N (Relion Novolin N) is a man-made form of a hormone that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Relion Novolin N is an intermediate-acting insulin that starts to work within 2 to 4 hours after injection, peaks in 4 to 12 hours, and keeps working for 12 to 18 hours.
Relion Novolin N is used to improve blood sugar control in adults and children with diabetes mellitus.
Relion Novolin N may also be used for purposes not listed in this medication guide.
Relion Novolin N indications
Relion Novolin N is an intermediate-acting recombinant human insulin indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus.
How should I use Relion Novolin N?
Use Relion Novolin N vials as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Relion Novolin N vials. Talk to your pharmacist if you have questions about this information.
- Check with your doctor about how you should use Relion Novolin N vials with regard to meals.
- If you will be using Relion Novolin N vials at home, a health care provider will teach you how to use it. Be sure you understand how to use Relion Novolin N vials. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Carefully rotate the vial as directed before each injection. This will ensure that the contents are evenly mixed. This insulin should look uniformly cloudy or milky.
- Do not use Relion Novolin N vials if it contains particles or clumps, is discolored, or if the vial is cracked or damaged.
- If you are mixing Relion Novolin N vials with another insulin, draw the other insulin into the syringe first. Inject the dose immediately after mixing, as directed by your doctor.
- Do NOT use Relion Novolin N vials in an insulin pump.
- Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into muscle or a vein.
- Injection sites within an injection area (abdomen, thigh, upper arm) must be rotated from one injection to the next.
- Be sure you have purchased the correct insulin. Insulin comes in a variety of containers, including vials, cartridges, and pens. Make sure that you understand how to properly measure and prepare your dose. If you have any questions about measuring and preparing your dose, contact your doctor or pharmacist for information.
- Relion Novolin N vials begins lowering blood sugar within 30 to 90 minutes after an injection. The peak effect occurs within 4 to 12 hours after a dose. The effect may last for up to 24 hours.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- It is very important to follow your insulin regimen exactly. Do NOT miss any doses. Ask your doctor for specific instructions to follow in case you ever miss a dose of insulin.
Ask your health care provider any questions you may have about how to use Relion Novolin N vials.
Uses of Relion Novolin N in details
Relion Novolin N is used to reduce high blood sugar (glucose) levels in patients with type 1 diabetes (condition in which the body does not produce insulin [a hormone that controls blood sugar levels]) and type 2 diabetes (condition in which the body does not use insulin normally).
Relion Novolin N description
Relion Novolin N (NPH) contains isophane human insulin.
Relion Novolin N dosage
Relion Novolin N Dosage
Generic name: Insulin human 100[iU] in 1mL
Dosage form: injection, suspension
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Important Administration Instructions
Inspect Relion Novolin N visually before use. It should not contain particulate matter and should appear uniformly cloudy after mixing. Do not use Relion Novolin N if particulate matter is seen.
Route of Administration
Relion Novolin N should only be administered subcutaneously.
Administer in the subcutaneous tissue of the abdominal wall, thigh, upper arm, or buttocks. To reduce the risk of lipodystrophy, rotate the injection site within the same region from one injection to the next.
Do not administer Relion Novolin N intravenously or intramuscularly and do not use Relion Novolin N in an insulin infusion pump.
Dosage Information
Individualize and adjust the dosage of Relion Novolin N based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal.
Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function or during acute illness.
Dosage Adjustment due to Drug Interactions
Dosage adjustment may be needed when Relion Novolin N is coadministered with certain drugs.
Dosage adjustment may be needed when switching from another insulin to Relion Novolin N.
Instructions for Mixing with Other Insulins
Relion Novolin N may be used with a prandial insulin if indicated. Relion Novolin N may be mixed with HUMULIN R or HUMALOG before injection.
- If Relion Novolin N is mixed with HUMULIN R, HUMULIN R should be drawn into the syringe first. Injection should occur immediately after mixing.
- If Relion Novolin N is mixed with HUMALOG, HUMALOG should be drawn into the syringe first. Injection should occur immediately after mixing.
More about Relion Novolin N (Relion Novolin N)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 1 Review - Add your own review/rating
Consumer resources
- Relion Novolin N
- Other brands: Novolin N, Relion Novolin N, Relion Novolin N Pen
Professional resources
- Relion Novolin N (FDA)
Related treatment guides
- Diabetes, Type 1
- Diabetes, Type 2
- Gestational Diabetes
Relion Novolin N interactions
See also:
What other drugs will affect Relion Novolin N?
Drugs That May Increase The Risk Of Hypoglycemia
The risk of hypoglycemia associated with Relion Novolin N use may be increased when co-administered with antidiabetic agents, salicylates, sulfonamide antibiotics, monoamine oxidase inhibitors, fluoxetine, disopyramide, fibrates, propoxyphene, pentoxifylline, ACE inhibitors, angiotensin II receptor blocking agents, and somatostatin analogs (e.g., octreotide). Dose adjustment and increased frequency of glucose monitoring may be required when Relion Novolin N is co-administered with these drugs.
Drugs That May Decrease The Blood Glucose Lowering Effect Of Relion Novolin N
The glucose lowering effect of Relion Novolin N may be decreased when co-administered with corticosteroids, isoniazid, niacin, estrogens, oral contraceptives, phenothiazines, danazol, diuretics, sympathomimetic agents (e.g., epinephrine, albuterol, terbutaline), somatropin, atypical antipsychotics, glucagon, protease inhibitors, and thyroid hormones. Dose adjustment and increased frequency of glucose monitoring may be required when Relion Novolin N is co-administered with these drugs.
Drugs That May Increase Or Decrease The Blood Glucose Lowering Effect Of Relion Novolin N
The glucose lowering effect of Relion Novolin N may be increased or decreased when co-administered with beta-blockers, clonidine, lithium salts, and alcohol. Pentamidine may cause hypoglycemia, which may sometimes be followed by hyperglycemia. Dose adjustment and increased frequency of glucose monitoring may be required when Relion Novolin N is co-administered with these drugs.
Drugs That May Blunt Signs And Symptoms Of Hypoglycemia
The signs and symptoms of hypoglycemia may be blunted when beta-blockers, clonidine, guanethidine, and reserpine are co-administered with Relion Novolin N.
Relion Novolin N side effects
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What are the possible side effects of Relion Novolin N?
The following adverse reactions are discussed elsewhere in the labeling:
- Hypoglycemia.
- Hypokalemia.
The following additional adverse reactions have been identified during post-approval use of Relion Novolin N. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or to establish a causal relationship to drug exposure.
Allergic Reactions
Some patients taking Relion Novolin N have experienced erythema, local edema, and pruritus at the site of injection. These conditions were usually self-limiting. Severe cases of generalized allergy (anaphylaxis) have been reported.
Peripheral Edema
Some patients taking Relion Novolin N have experienced sodium retention and edema, particularly if previously poor metabolic control is improved by intensified insulin therapy.
Lipodystrophy
Administration of insulin subcutaneously, including Relion Novolin N, has resulted in lipoatrophy (depression in the skin) or lipohypertrophy (enlargement or thickening of tissue) in some patients.
Weight gain
Weight gain has occurred with some insulin therapies including Relion Novolin N and has been attributed to the anabolic effects of insulin and the decrease in glycosuria.
Immunogenicity
Development of antibodies that react with human insulin have been observed with all insulin, including Relion Novolin N.
Relion Novolin N contraindications
See also:
What is the most important information I should know about Relion Novolin N?
Take care to keep your blood sugar from getting too low, causing hypoglycemia. Symptoms of low blood sugar may include headache, nausea, hunger, confusion, drowsiness, weakness, dizziness, blurred vision, fast heartbeat, sweating, tremor, or trouble concentrating. Carry a piece of non-dietetic hard candy or glucose tablets with you in case you have low blood sugar. Also be sure your family and close friends know how to help you in an emergency.
Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, loss of appetite, increased urination, nausea, vomiting, drowsiness, dry skin, and dry mouth. Check your blood sugar levels and ask your doctor how to adjust your insulin doses if needed.
Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.
Relion Novolin N is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
Active ingredient matches for Relion Novolin N:
List of Relion Novolin N substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Humulin N (Aruba, Bahamas, Bangladesh, Barbados, Bermuda, Bosnia & Herzegowina, Bulgaria, Canada, Cayman Islands, Colombia, Costa Rica, Croatia (Hrvatska), Czech Republic, Dominican Republic, El Salvador, Estonia, Ethiopia, Georgia, Guatemala, Haiti, Honduras, Hong Kong, Hungary, Israel, Jamaica, Japan, Latvia, Lithuania, Malaysia, Mexico, Netherlands Antilles, Nicaragua, Panama, Peru, Philippines, Poland, Romania, Singapore, Slovakia, Slovenia, South Africa, Sri Lanka, Taiwan, Thailand, Trinidad & Tobago, Turkey, United States, Vietnam) | |
| Humulin N / vial 100 IU/1 mL x 1 mL (Eli Lilly) | |
| Humulin N / vial 100 IU/1 mL x 10 mL (Eli Lilly) | |
| Humulin N / cartridge 100 IU/1 mL x 3 mL (Eli Lilly) | |
| Humulin N / NPH / Vial 100 u/1 mL x 10 mL (Eli Lilly) | $ 28.80 |
| Humulin N / NPH / Cartridge 100 IU/1 mL x 3 mL (Eli Lilly) | $ 11.13 |
| Humulin N / cartridge 100 IU/1 mL x 3 mL x 5's (Eli Lilly) | |
| Humulin N / cartridge 100 u/1 mL x 3 mL x 5's (Eli Lilly) | |
| Humulin N / vial 100 u/1 mL x 10 mL (Eli Lilly) | |
| Humulin N / NPH inj 100 u/mL / cartridge 3 mL x 5 x 1's (Eli Lilly) | |
| Humulin N / NPH inj 100 u/mL / vial 10 mL x 1's (Eli Lilly) | |
| HumuLIN N KwikPen | |
| Humulin N Pen | |
| Injectable; Injection; Insulin Biosynthetic Human BR 100 IU / ml | |
| Humulin N Pens | |
| Humulin N Vials | |
| Iletin II NPH Pork | |
| Iletin NPH | |
| Injectable; Injection; Insulin Isophane NPH 100 units / ml (Eli Lilly and Company (India) Pvt Ltd) | |
| Iletin NPH 40 iu Injection (Eli Lilly and Company (India) Pvt Ltd) | $ 0.11 |
| ILETIN-NPH | |
| ILETIN-NPH 40IU INJECTION 1 vial / 10 ML injection each (Eli Lilly and Company India Pvt Ltd) | $ 1.09 |
| INSULIN (NND) | |
| INSULIN 40 IU INJECTION 1 vial / 10 ML injection each (Novo Nordisk India Pvt Ltd) | $ 0.05 |
| INSULIN (RANBAXY) | |
| INSULIN 40 IU INJECTION 1 vial / 10 ML injection each (Ranbaxy Laboratories Ltd) | $ 1.70 |
| Insulin B. Braun Ratiopharm Basal | |
| Injectable; Injection; Insulin Isophane 100 IU / ml | |
| Injectable; Injection; Insulin Isophane 40 IU / ml | |
| Insulin Isophane | |
| Insulin Isophane InnoLets | |
| Insulin Isophane Pens | |
| Insulin Isophane Vials | |
| Insulin Purified NPH Pork | |
| LONGACT | |
| LONGACT 40IU INJECTION 1 vial / 10 ML injection each (USV Ltd) | $ 0.88 |
| LONGACT TABLET 1 strip / 10 tablets each (Mech Pharmaceuticals) | $ 0.61 |
| Longact Tablet (Mech Pharmaceuticals) | $ 0.06 |
| NovoLIN N FlexPen | |
| NovoLIN N FlexPen ReliOn | |
| Novolin N Innolet | |
| Novolin N InnoLets | |
| Novolin N PenFill | |
| Injectable; Injection; Insulin Isophane Suspension Human recombinant; Insulin Isophane Suspension Human semisynthetic purified 100 units / ml | |
| Novolin N Pens | |
| NovoLIN N ReliOn | |
| Novolin N Vials | |
| NPH Insulin | |
| Injectable; Injection; Insulin Isophane Suspension Beef 40 units / ml | |
| Injectable; Injection; Insulin Isophane Suspension Beef 100 units / ml | |
| RECOSULIN N | |
| RECOSULIN N 40IU INJECTION 1 vial / 10 ML injection each (Shreya Life Sciences Pvt Ltd) | $ 1.79 |
See 44 substitutes for Relion Novolin N | |
Reviews
The results of a survey conducted on ndrugs.com for Relion Novolin N are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Relion Novolin N. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
